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| Language | English |
| Format | PDF (Premium Digital) |
| Ownership | Permanent download — yours forever |
Tissue-Specific Estrogen Action by Kenneth S Korach
Nuclear hormone receptors are not only important drug targets, but have also been the focus of decades of active and highly insightful research. Ten years ago, a review on nuclear receptors was entitled The Second Decade and a special issue of Molecular Endocrinology in 2005 dealt with the results of these research efforts. The consensus from nuclear receptor research was of course that the signaling pathways mediated by these receptors warrant further research, even though in principle they appeared to represent the most immediate, seemingly simple signaling pathway from hormone (ligand) binding to gene expression changes. In nuclear receptor molecular biology, estrogen receptor research has additional unique facets: since the discovery of ethinyl estradiol by Inhoffen and Hohlweg in the laboratories of Schering AG in the 1930s--and therefore several decades longer than nuclear receptor - searchitself--estrogenreceptorshavebeentargetsofwidelyused, orally administered drugs. Thus, accumulating clinical experience on estrogen action in vivo helps to support the progress in molecular biological research.| ISBN 13 | 9783642421037 |
|---|---|
| ISBN 10 | 3642421032 |
| Author | Kenneth S Korach |
| Series | Ernst Schering Foundation Symposium Proceedings |
| Condition | New |
| Binding Type | Paperback |
| Publisher | Springer |
| Year published | 2014-11-28 |
| Number of pages | 181 |
| Cover note | Book picture is for illustrative purposes only, actual binding, cover or edition may vary. |
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