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| Language | English |
| Format | PDF (Premium Digital) |
| Ownership | Permanent download — yours forever |
Therapeutic Hypothermia by Samuel Tisherman
Samuel A. Tisherman, MD', Fritz Sterz, MD ' niversit of Pittsburgh, Pittsburgh, PA, USA 2 edical University of Vienna, Vienna, Austria The use of hypothermia for a variety of therapeutic purposes has a long and erratic history. Hippocrates recommended the use of topical cooling to stop bleeding. Fay used cooling of the extremities for patients with tumors in the 1930s. It wasn't until the 1950s, when the effects of hypothermia on systemic oxygen metabolism became better defined, that systemic hypothermia became a commonly used modality, particularly for cardiac surgery. Hypothermia was used for protection (treatment before the insult) and preservation (treatment during the insult) of the heart and entire organism during planned operative ischemia. Shortly thereafter, attempts were made to use hypothermia for resuscitation (treatment after the insult) from cardiac arrest and for management of head trauma. At that time, it was felt that moderate hypothermia (28-32OC) was needed. This was difficult to achieve and manage. Multiple complications were noted. Consequently, therapeutic, resuscitative hypothermia lay dormant for many years while mild (32-35 C) to moderate hypothermia became common for many cardiothoracic and neurosurgical procedures. In the early 1990s, it was found that mild hypothermia, even after cardiac arrest, had benefit for the brain. Similar results were found with head trauma. This lead to a burst of enthusiasm for research into resuscitative hypothermia for a variety of insults, most of which have tissue ischemia as a major component.| SKU | NLS9781441937933 |
|---|---|
| ISBN 13 | 9781441937933 |
| ISBN 10 | 1441937935 |
| Author | Samuel Tisherman |
| Series | Molecular And Cellular Biology Of Critical Care Medicine Ser |
| Condition | New |
| Binding Type | Paperback |
| Publisher | Springer-Verlag New York Inc. |
| Year published | 2010-11-23 |
| Number of pages | 258 |
| Cover note | Book picture is for illustrative purposes only, actual binding, cover or edition may vary. |
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