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| Language | English |
| Format | PDF (Premium Digital) |
| Ownership | Permanent download — yours forever |
The Origins of Depression: Current Concepts and Approaches by Aj Rush
3 and a fraction mayor may not respond to treatment. On the behavioral level, animal research shows that a variety of experimental conditions can induce de- pression. The same is true in the field of treatment, where pharmacologically highly different drugs can equally alleviate depression in animals and hu- mans. The question as to whether this is due to a heterogeneity of depressive subjects based on different pathogenetic mechanisms is open to discussion. We can look for common features of all possible causal factors in the hope of finding a single basic mechanism. Many divergent findings may also be ex- plained as peripheral changes of a highly complicated dynamic system. In the field of psychopharmacology, a circular reasoning has become evident in the sense that originally the clinical antidepressive response was founded on empirical grounds only. In a second step, an attempt was made to characterize some clinically active compounds pharmacologically, and in a third, further compounds were developed based on aspects of the pharmaco- logical profiles. Moreover, the post hoc development of a pharmacological screening method has the serious disadvantage of delaying breakthroughs into new fields.| ISBN 13 | 9783642691317 |
|---|---|
| ISBN 10 | 3642691315 |
| Author | J Angst |
| Series | Dahlem Workshop Report |
| Condition | New |
| Binding Type | Paperback |
| Publisher | Springer |
| Year published | 2011-11-23 |
| Number of pages | 474 |
| Cover note | Book picture is for illustrative purposes only, actual binding, cover or edition may vary. |
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