The Link Between Inflammation and Cancer by Angus G Dalgleish ISBN 9781441938817
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The Link Between Inflammation and Cancer by Angus G Dalgleish ISBN 9781441938817

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The Link Between Inflammation and Cancer by Angus G Dalgleish

A link between inflammation and cancer has been established many years ago, yet it is only recently that the potential significance of this connection has become apparent. Although several examples of chronic inflammatory conditions, often induced by persistent irritation and/or infection, developing into cancer have been known for some time, there has been a notable resistance to contemplate the possibility that this association may apply in a causative way to other cancers. Examples for such progression from chronic inflammation to cancer are colon carcinoma developing with increased frequency in patients with ulcerative colitis, and the increased incidence of bladder cancer in patients suffering from chronic Schistosoma infection. Inflammation and cancer have been recognized to be linked in another context for many years, i.e., with regards to pathologies resembling chronic lacerations or 'wounds that do not heal.' More recently, the immunology of wound healing has given us clues as to the mechanistic link between inflammation and cancer, in as much as wounds and chronic inflammation turn off local cell-mediated immune responses and switch on growth factor release as well the growth of new blood vessels - angiogenesis. Both of these are features of most types of tumours, which suggest that tumours may require an immunologically shielded milieu and a growth factor-rich environment.

Book details

SKU NLS9781441938817
ISBN 13 9781441938817
ISBN 10 1441938818
Author Angus G Dalgleish
Series Cancer Treatment And Research
Condition New
Binding Type Paperback
Publisher Springer-Verlag New York Inc.
Year published 2010-12-08
Number of pages 254
Cover note Book picture is for illustrative purposes only, actual binding, cover or edition may vary.

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