Techniques in Somatic Cell Genetics by Jerry W Shay ISBN 9781468442731
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Techniques in Somatic Cell Genetics by Jerry W Shay ISBN 9781468442731

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Techniques in Somatic Cell Genetics by Jerry W Shay

Somatic cell genetics is an exciting and rapidly expanding field of research. Since descriptions of the major experimental techniques in the field are scattered throughout various journals and other publications, there is a real need for a single reference source for both established investigators and students in the field. In addition, technical reports are frequently abridged such that many researchers are discouraged from attempting to adopt the appropriate methodology. This book, therefore, describes in detail the many recent technical advances in such areas of somatic cell genetics as transfer mediated by liposomes, erythrocyte ghosts, chromosomes, micro cells, mito- chondria, and isolated nuclear DNA. These techniques have increased our understanding of the organization and regulation of eukaryotic cells. The production of antibiotic-resistant cell lines and their use in studying cytoplasmic inheritance are also included. Evidence for the cytoplasmic regulation of nuclear gene expression in eukaryotic cells is rapidly accumu- lating following the characterization of cytoplasmic mutations. The produc- tion of nuclear-coded mutations, their use in standard cell hybridization, and recent advances in techniques for fusing whole cells or cell components are also described.

Book details

SKU NLS9781468442731
ISBN 13 9781468442731
ISBN 10 1468442732
Author Jerry W Shay
Condition New
Binding Type Paperback
Publisher Springer-Verlag New York Inc.
Year published 2012-04-26
Number of pages 568
Cover note Book picture is for illustrative purposes only, actual binding, cover or edition may vary.

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