{"product_id":"recombinant-protein-production-with-prokaryotic-and-eukaryotic-cells-a-comparative-view-on-host-physiology-by-otto-wilhelm-merten-nls9789048157563","title":"Recombinant Protein Production with Prokaryotic and Eukaryotic Cells. A Comparative View on Host Physiology by Otto-Wilhelm Merten ISBN 9789048157563","description":"\u003cp\u003e\u003cb\u003eRecombinant Protein Production with Prokaryotic and Eukaryotic Cells. A Comparative View on Host Physiology by Otto-Wilhelm Merten\u003c\/b\u003e\u003c\/p\u003e\n More then 20 years have passed now since the first recombinant protein producing microorganisms have been developed. In the meanwhile, numerous proteins have been produced in bacteria, yeasts and filamentous fungi, as weIl as higher eukaryotic cells, and even entire plants and animals. Many recombinant proteins are on the market today, and some of them reached substantial market volumes. On the first sight one would expect the technology - including the physiology of the host strains - to be optimised in detail after a 20 year's period of development. However, several constraints have limited the incentive for optimisation, especially in the pharmaceutical industry like the urge to proceed quickly or the requirement to define the production parameters for registration early in the development phase. The additional expenses for registration of a new production strain often prohibits a change to an optimised strain. A continuous optimisation of the entire production process is not feasible for the same reasons. \u003ch3\u003eBook details\u003c\/h3\u003e\u003ctable style=\"border-collapse: collapse; width: 100%; \"\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth style=\"text-align: left; padding: 6px 10px; border: 1px solid #ddd; \"\u003eSKU\u003c\/th\u003e\n\u003ctd style=\"padding: 6px 10px; border: 1px solid #ddd; \"\u003eNLS9789048157563\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth style=\"text-align: left; padding: 6px 10px; border: 1px solid #ddd; \"\u003eISBN 13\u003c\/th\u003e\n\u003ctd style=\"padding: 6px 10px; border: 1px solid #ddd; \"\u003e9789048157563\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth style=\"text-align: left; padding: 6px 10px; border: 1px solid #ddd; \"\u003eISBN 10\u003c\/th\u003e\n\u003ctd style=\"padding: 6px 10px; border: 1px solid #ddd; \"\u003e9048157560\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth style=\"text-align: left; padding: 6px 10px; border: 1px solid #ddd; \"\u003eAuthor\u003c\/th\u003e\n\u003ctd style=\"padding: 6px 10px; border: 1px solid #ddd; \"\u003eOtto-Wilhelm Merten\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth style=\"text-align: left; padding: 6px 10px; border: 1px solid #ddd; \"\u003eCondition\u003c\/th\u003e\n\u003ctd style=\"padding: 6px 10px; border: 1px solid #ddd; \"\u003eNew\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth style=\"text-align: left; padding: 6px 10px; border: 1px solid #ddd; \"\u003eBinding Type\u003c\/th\u003e\n\u003ctd style=\"padding: 6px 10px; border: 1px solid #ddd; \"\u003ePaperback\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth style=\"text-align: left; padding: 6px 10px; border: 1px solid #ddd; \"\u003ePublisher\u003c\/th\u003e\n\u003ctd style=\"padding: 6px 10px; border: 1px solid #ddd; \"\u003eSpringer\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth style=\"text-align: left; padding: 6px 10px; border: 1px solid #ddd; \"\u003eYear published\u003c\/th\u003e\n\u003ctd style=\"padding: 6px 10px; border: 1px solid #ddd; \"\u003e2010-12-01\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth style=\"text-align: left; padding: 6px 10px; border: 1px solid #ddd; \"\u003eNumber of pages\u003c\/th\u003e\n\u003ctd style=\"padding: 6px 10px; border: 1px solid #ddd; \"\u003e400\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth style=\"text-align: left; padding: 6px 10px; border: 1px solid #ddd; \"\u003eCover note\u003c\/th\u003e\n\u003ctd style=\"padding: 6px 10px; border: 1px solid #ddd; \"\u003eBook picture is for illustrative purposes only, actual binding, cover or edition may vary.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e","brand":"Springer","offers":[{"title":"Default Title","offer_id":67735436722421,"sku":"NLS9789048157563","price":39.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0795\/8632\/8821\/files\/9789048157563.jpg?v=1792241836","url":"https:\/\/arbiyas.com\/products\/recombinant-protein-production-with-prokaryotic-and-eukaryotic-cells-a-comparative-view-on-host-physiology-by-otto-wilhelm-merten-nls9789048157563","provider":"Arbiyas","version":"1.0","type":"link"}