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| Language | English |
| Format | PDF (Premium Digital) |
| Ownership | Permanent download — yours forever |
RAS Family GTPases by Channing Der
Since 1982, Ras proteins have been the subject of intense research investigation by the biomedical research community. The wide interest in Ras has been stimulated for three key reasons.
First, their frequent mutational activation in human cancers establishes Ras proteins as important mediators of oncogenesis and targets for anti-cancer drug discovery. Second, Ras proteins act as signalling nodes activated by diverse extracellular stimuli, and activated Ras in turn regulates a diversity of cytoplasmic signalling networks. Third, Ras proteins are founding members of a large superfamily of Ras-related small GTPases. Over 150 Ras-related small GTPases are found in the human genome, with orthologs found in all vertebrate species and invertebrates.
This book features chapters by leading investigators in the field that highlight the current state-of-the art in Ras biochemistry, structure and biology. This book is an excellent reference for students in the biomedical sciences and for investigators in the field.
| SKU | NLS9781402043284 |
|---|---|
| ISBN 13 | 9781402043284 |
| ISBN 10 | 1402043287 |
| Author | Channing Der |
| Series | Proteins And Cell Regulation |
| Condition | New |
| Binding Type | Hardback |
| Publisher | Springer-Verlag New York Inc. |
| Year published | 2006-09-13 |
| Number of pages | 397 |
| Cover note | Book picture is for illustrative purposes only, actual binding, cover or edition may vary. |
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"I compared Kindle vs this store. Kindle is cheaper monthly but you don't own anything. Here I paid once and the PDF is mine for life. Highly recommend."
"Left Kindle behind after they removed a book I was reading mid-series. With this PDF, nobody can take it away from me. True ownership feels good."
"Was skeptical about paying $18.95 when Kindle shows $3.99, but then I did the math — Kindle Unlimited is $143/year! This is way better value long term."
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