{"product_id":"purine-metabolism-in-man-by-oded-sperling-nls9781468432961","title":"Purine Metabolism in Man by Oded Sperling ISBN 9781468432961","description":"\u003cp\u003e\u003cb\u003ePurine Metabolism in Man by Oded Sperling\u003c\/b\u003e\u003c\/p\u003e\n Gout and urie acid lithiasis are known to have affected mankind for thousands of years. It is only recently, however, that great progress has been made in the understanding of the processes involved in purine metabolism and its disorders in man. The key enzymes active in the various pathways of purine synthesis and degradation have become known and their properties are the subject of intensive study. Major contributions to the knowledge of normal purine metabolism in man have derived from the study of inborn errors in patients with purine disorders, specifically complete and partial hypoxanthine-guanine phosphoribosyltransferase deficiency. Mutations of other enzymes involved in purine metabolism are being discovered. A great step forward has been made in the treatment of gout with the introduction of uricosuric drugs and more recently of the hypoxanthine analogue allopurinol, a synthetic xanthine oxidase inhibitor. Furthermore, the complex nature of the renal handling of urie acid excretion, although still posing difficult problems, appears to approach clari- fication. \u003ch3\u003eBook details\u003c\/h3\u003e\u003ctable style=\"border-collapse: collapse; width: 100%; \"\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth style=\"text-align: left; padding: 6px 10px; border: 1px solid #ddd; \"\u003eSKU\u003c\/th\u003e\n\u003ctd style=\"padding: 6px 10px; border: 1px solid #ddd; \"\u003eNLS9781468432961\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth style=\"text-align: left; padding: 6px 10px; border: 1px solid #ddd; \"\u003eISBN 13\u003c\/th\u003e\n\u003ctd style=\"padding: 6px 10px; border: 1px solid #ddd; \"\u003e9781468432961\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth style=\"text-align: left; padding: 6px 10px; border: 1px solid #ddd; \"\u003eISBN 10\u003c\/th\u003e\n\u003ctd style=\"padding: 6px 10px; border: 1px solid #ddd; \"\u003e1468432966\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth style=\"text-align: left; padding: 6px 10px; border: 1px solid #ddd; \"\u003eAuthor\u003c\/th\u003e\n\u003ctd style=\"padding: 6px 10px; border: 1px solid #ddd; \"\u003eOded Sperling\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth style=\"text-align: left; padding: 6px 10px; border: 1px solid #ddd; \"\u003eSeries\u003c\/th\u003e\n\u003ctd style=\"padding: 6px 10px; border: 1px solid #ddd; \"\u003eAdvances In Experimental Medicine And Biology\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth style=\"text-align: left; padding: 6px 10px; border: 1px solid #ddd; \"\u003eCondition\u003c\/th\u003e\n\u003ctd style=\"padding: 6px 10px; border: 1px solid #ddd; \"\u003eNew\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth style=\"text-align: left; padding: 6px 10px; border: 1px solid #ddd; \"\u003eBinding Type\u003c\/th\u003e\n\u003ctd style=\"padding: 6px 10px; border: 1px solid #ddd; \"\u003ePaperback\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth style=\"text-align: left; padding: 6px 10px; border: 1px solid #ddd; \"\u003ePublisher\u003c\/th\u003e\n\u003ctd style=\"padding: 6px 10px; border: 1px solid #ddd; \"\u003eSpringer-Verlag New York Inc.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth style=\"text-align: left; padding: 6px 10px; border: 1px solid #ddd; \"\u003eYear published\u003c\/th\u003e\n\u003ctd style=\"padding: 6px 10px; border: 1px solid #ddd; \"\u003e2013-02-25\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth style=\"text-align: left; padding: 6px 10px; border: 1px solid #ddd; \"\u003eNumber of pages\u003c\/th\u003e\n\u003ctd style=\"padding: 6px 10px; border: 1px solid #ddd; \"\u003e366\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth style=\"text-align: left; padding: 6px 10px; border: 1px solid #ddd; \"\u003eCover note\u003c\/th\u003e\n\u003ctd style=\"padding: 6px 10px; border: 1px solid #ddd; \"\u003eBook picture is for illustrative purposes only, actual binding, cover or edition may vary.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e","brand":"Springer-Verlag New York Inc.","offers":[{"title":"Default Title","offer_id":67735406280949,"sku":"NLS9781468432961","price":39.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0795\/8632\/8821\/files\/9781468432961.jpg?v=1792241180","url":"https:\/\/arbiyas.com\/products\/purine-metabolism-in-man-by-oded-sperling-nls9781468432961","provider":"Arbiyas","version":"1.0","type":"link"}