Protein Quality Control in Neurodegenerative Diseases by Richard I Morimoto | ISBN-13 9783642279270
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Protein Quality Control in Neurodegenerative Diseases by Richard I Morimoto | ISBN-13 9783642279270

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Protein Quality Control in Neurodegenerative Diseases by Richard I Morimoto

The health of the proteome depends upon protein quality control to regulate the proper synthesis, folding, translocation, and clearance of proteins. The cell is challenged constantly by environmental and physiological stress, aging, and the chronic expressions of disease associated misfolded proteins. Substantial evidence supports the hypothesis that the expression of damaged proteins initiates a cascade of molecular events that leads to Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, Huntington's disease, and other diseases of protein conformation.

Book details

ISBN 13 9783642279270
ISBN 10 3642279279
Author Richard I Morimoto
Series Research And Perspectives In Alzheimer's Disease
Condition New
Binding Type Hardback
Publisher Springer
Year published 2012-12-12
Number of pages 136
Cover note Book picture is for illustrative purposes only, actual binding, cover or edition may vary.

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