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| Language | English |
| Format | PDF (Premium Digital) |
| Ownership | Permanent download — yours forever |
Explore Pharmacodynamic Models of Selected Toxic Chemicals in Man by Mc Thorne by Mc Thorne, a valuable resource for readers seeking subject knowledge, key concepts, and a deeper understanding of the topic.
Pharmacodynamic Models of Selected Toxic Chemicals in Man by Mc Thorne These volumes present the results of two studies undertaken for the Directorate General of Employment, Social Affairs and Education of the Commission of the European Communities. The aim was to review available data concerning the metabolism of a selection of toxic chemi- cals in man and to develop mathematical models representing this meta- bolism. Volume 1 is the report from the first study and presents re- views of the data for each of the substances and proposes models for their metabolic behaviour. Volume 2 is the report of the second study and contains a review of new data relevant to the development of meta- bolic models for each substance. The modelling of uptake and retention by the two major routes of uptake (the respiratory system and the gas- trointestinal tract) is also reviewed. The implementation of the models in a computer code is described and results are presented illus- trating organ concentrations and rates of excretion for typical regimes of exposure. vi 1 Foreword This report contains the results of a study undertaken by Associated Nuclear Services (ANS) for the Directorate General of Employment, Social Affairs and Education of the Commission of the European Communities (CEC). This study was entitled Models for the Metabolism of Chemical Carcinogens in Man. vii 2 Summary This report includes results of a review of the metabolism of selected actual and potential human carcinogens and proposals for pharmacokinetic models to represent that metabolism.
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"Kindle Unlimited kept raising prices. This is a one-time purchase and the file is permanently on my iPad. Best decision I've made for my reading habit."
"I compared Kindle vs this store. Kindle is cheaper monthly but you don't own anything. Here I paid once and the PDF is mine for life. Highly recommend."
"Left Kindle behind after they removed a book I was reading mid-series. With this PDF, nobody can take it away from me. True ownership feels good."
"Was skeptical about paying $18.95 when Kindle shows $3.99, but then I did the math — Kindle Unlimited is $143/year! This is way better value long term."
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