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| Language | English |
| Format | PDF (Premium Digital) |
| Ownership | Permanent download — yours forever |
PAS Proteins: Regulators and Sensors of Development and Physiology by Stephen T Crews
The subject of this volume is a comprehensive examination of the biochemistry and biology of all classes of known PAS proteins, with the intention that readers will find insight into their own work and ideas from study of the multitude of PAS protein functions. PAS proteins control numerous physiological and developmental events, and span phylogeny from bacteria to man. Bacterial and plant PAS proteins act as sensors of environmental stimuli, including light, oxygen, and energy status.
Not surprising, given these roles, there is intense investigation of the roles of bHLH-PAS proteins in issues of human health including: (1) cancer induction, (2) cancer growth and vascularity, (3) birth defects, including Down syndrome, (4) appetite control and obesity, (5) sleep rhythm disorders, and (6) mental health disorders such as social interactions and learning.
PAS proteins encompass many fields of biology, and scientists who work in these fields (circadian rhythms, oxygen regulation, toxin metabolism, bacterial sensors, and development) are an audience, particularly those who actively work on PAS proteins and researchers interested in transcriptional control, signal transduction, and evolution.
| SKU | NLS9781461351153 |
|---|---|
| ISBN 13 | 9781461351153 |
| ISBN 10 | 1461351154 |
| Author | Stephen T Crews |
| Condition | New |
| Binding Type | Paperback |
| Publisher | Springer-Verlag New York Inc. |
| Year published | 2012-10-21 |
| Number of pages | 263 |
| Cover note | Book picture is for illustrative purposes only, actual binding, cover or edition may vary. |
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