{"product_id":"multi-drug-resistance-in-cancer-by-jun-zhou-nls9781607614159","title":"Multi-Drug Resistance in Cancer by Jun Zhou ISBN 9781607614159","description":"\u003cp\u003e\u003cb\u003eMulti-Drug Resistance in Cancer by Jun Zhou\u003c\/b\u003e\u003c\/p\u003e Chemotherapy is one of the major treatment options for cancer patients; however, the efficacy of chemotherapeutic management of cancer is severely limited by multidrug resistance, in that cancer cells become simultaneously resistant to many structurally and mechanistically unrelated drugs. In the past three decades, a number of mechanisms by which cancer cells acquire multidrug resistance have been discovered. In addition, the development of agents or strategies to overcome resistance has been the subject of intense study. This book contains comprehensive and up-to-date reviews of multidrug resistance mechanisms, from over-expression of ATP-binding cassette drug transporters such as P-glycoprotein, multidrug resistance-associated proteins, and breast cancer resistance p- tein to the drug ratio-dependent antagonism and the paradigm of cancer stem cells. The book also includes strategies to overcome multidrug resistance, from the development of compounds that inhibit drug transporter function to the modulation of transporter expression. In addition, this book contains techniques for the detection and imaging of drug transporters, methods for the investigation of drug resistance in animal models, and strategies to evaluate the efficacy of resistance reversal agents. The book intends to provide a state-of-the-art collection of reviews and methods for both basic and clinician investigators who are interested in cancer multidrug resistance mechanisms and reversal strategies. Tianjin, China Jun Zhou v Contents Preface. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . v Contributors. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ix 1 MultidrugResistance in Cancer . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 Bruce C. Baguley 2 Multidrug Resistance in Oncology and Beyond: From Imaging of Drug Efflux Pumps to Cellular Drug Targets . . . . . . . . . . . . . . . . . . . . . . . . . .\u003ch3\u003eBook details\u003c\/h3\u003e\u003ctable style=\"border-collapse:collapse;width:100%;\"\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth style=\"text-align:left;padding:6px 10px;border:1px solid #ddd;\"\u003eSKU\u003c\/th\u003e\n\u003ctd style=\"padding:6px 10px;border:1px solid #ddd;\"\u003eNLS9781607614159\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth style=\"text-align:left;padding:6px 10px;border:1px solid #ddd;\"\u003eISBN 13\u003c\/th\u003e\n\u003ctd style=\"padding:6px 10px;border:1px solid #ddd;\"\u003e9781607614159\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth style=\"text-align:left;padding:6px 10px;border:1px solid #ddd;\"\u003eISBN 10\u003c\/th\u003e\n\u003ctd style=\"padding:6px 10px;border:1px solid #ddd;\"\u003e1607614154\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth style=\"text-align:left;padding:6px 10px;border:1px solid #ddd;\"\u003eAuthor\u003c\/th\u003e\n\u003ctd style=\"padding:6px 10px;border:1px solid #ddd;\"\u003eJun Zhou\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth style=\"text-align:left;padding:6px 10px;border:1px solid #ddd;\"\u003eSeries\u003c\/th\u003e\n\u003ctd style=\"padding:6px 10px;border:1px solid #ddd;\"\u003eMethods In Molecular Biology\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth style=\"text-align:left;padding:6px 10px;border:1px solid #ddd;\"\u003eCondition\u003c\/th\u003e\n\u003ctd style=\"padding:6px 10px;border:1px solid #ddd;\"\u003eNew\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth style=\"text-align:left;padding:6px 10px;border:1px solid #ddd;\"\u003eBinding Type\u003c\/th\u003e\n\u003ctd style=\"padding:6px 10px;border:1px solid #ddd;\"\u003eHardback\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth style=\"text-align:left;padding:6px 10px;border:1px solid #ddd;\"\u003ePublisher\u003c\/th\u003e\n\u003ctd style=\"padding:6px 10px;border:1px solid #ddd;\"\u003eHumana Press Inc.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth style=\"text-align:left;padding:6px 10px;border:1px solid #ddd;\"\u003eYear published\u003c\/th\u003e\n\u003ctd style=\"padding:6px 10px;border:1px solid #ddd;\"\u003e2009-11-18\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth style=\"text-align:left;padding:6px 10px;border:1px solid #ddd;\"\u003eNumber of pages\u003c\/th\u003e\n\u003ctd style=\"padding:6px 10px;border:1px solid #ddd;\"\u003e492\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth style=\"text-align:left;padding:6px 10px;border:1px solid #ddd;\"\u003eCover note\u003c\/th\u003e\n\u003ctd style=\"padding:6px 10px;border:1px solid #ddd;\"\u003eBook picture is for illustrative purposes only, actual binding, cover or edition may vary.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e","brand":"Humana Press Inc.","offers":[{"title":"Default Title","offer_id":67722487365877,"sku":"NLS9781607614159","price":39.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0795\/8632\/8821\/files\/9781607614159.jpg?v=1792155265","url":"https:\/\/arbiyas.com\/products\/multi-drug-resistance-in-cancer-by-jun-zhou-nls9781607614159","provider":"Arbiyas","version":"1.0","type":"link"}