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| Language | English |
| Format | PDF (Premium Digital) |
| Ownership | Permanent download — yours forever |
Molecular Oncology: Underlying Mechanisms and Translational Advancements by Ammad Ahmad Farooqi
Cancer is a multifaceted and genomically complex disease and data obtained through high throughput technologies has provided near complete resolution of the landscape of how genomic, genetic and epigenetic mutations in cancerous cells effectively influence homeostasis of signaling networks within these cells, between cancerous cells, tumor microenvironment and at the organ level. Increasingly sophisticated information has helped us in developing a better understanding of the underlying mechanisms of cancer, and it is now known that intra-tumor genetic heterogeneity, cellular plasticity, dysregulation of spatio-temporally controlled signaling cascades, and loss of apoptosis are contributory in cancer development, progression and the development of resistance against different therapeutics. It is becoming progressively more understandable that earlier detection of pre-existing or emerging resistance against different therapeutics may prove to be helpful in personalizing the use of targeted cancer therapy.| ISBN 13 | 9783319850573 |
|---|---|
| ISBN 10 | 3319850571 |
| Author | Ammad Ahmad Farooqi |
| Condition | New |
| Binding Type | Paperback |
| Publisher | Springer International Publishing AG |
| Year published | 2018-07-21 |
| Number of pages | 302 |
| Cover note | Book picture is for illustrative purposes only, actual binding, cover or edition may vary. |
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