Molecular Biology and Pathogenesis of Coronaviruses by P J Rottier ISBN 9781461593751
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Molecular Biology and Pathogenesis of Coronaviruses by P J Rottier ISBN 9781461593751

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Molecular Biology and Pathogenesis of Coronaviruses by P J Rottier

The present volume contains the Proceedings of an EMBO Workshop organized in June 1983 by the Institute of Virology, Veterinary Faculty, State University of Utrecht, The Netherlands. Some 70 scientists from 11 countries followed the invitation to present and discuss their recent data on the structure, replication, genetics and pathogenesis of coronaviruses. It was the second international meeting on these viruses; the Workshop, which was held in Zeist near Utrecht followed the example of the Wuerzburg symposium of October 1980. At that time it became clear that coronaviruses are unique in many respects. Once a group of viruses that were defined merely on the basis of their characteristic peplomer morphology, Coronaviridae family members are known today - to be constructed from essentially three polypeptides - to use a "nested set" of 5-6 subgenomic mRNAs in the expression of their large, positive and single stranded RNA genome, - to generate these subgenomic RNAs through specific fusion of non­ contiguous sequences, - to mature by budding from intracellular membranes, - to cause persistent infection with neurological involvement and sometimes immunopathological conditons. These and many other findings have been established only very recently. The articles collected in this book reveal and/or further detail these findings. Since these Proceedings contain the combined scientific presentations of representatives from virtually all laboratories engaged in the field, they provide a fairly comprehensive review of the state of the art in corona­ virology.

Book details

SKU NLS9781461593751
ISBN 13 9781461593751
ISBN 10 1461593751
Author P J Rottier
Series Advances In Experimental Medicine And Biology
Condition New
Binding Type Paperback
Publisher Springer-Verlag New York Inc.
Year published 2012-11-25
Number of pages 409
Cover note Book picture is for illustrative purposes only, actual binding, cover or edition may vary.

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