Immunoregulation by Nicola Fabris ISBN 9781468445497
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Immunoregulation by Nicola Fabris ISBN 9781468445497

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Immunoregulation by Nicola Fabris

Immunoregulation is one of the areas which has witnessed the most explosive advances of immunology during the past decade. It is in this area that the current view of the immune system has arisen and developed. There is indeed little doubt that immune reactions are primarily determined by messages which are genera ted within the immune system and passed among different types of immunologie cells. This cell communication not only determines the type, intensity and duration of the response after perturbation of the immune system by exogenous antigens, but it is also essential for preventing autoimmune reactions and their clinical conse- quences. In order to assure aperfect balance within the enormous com- plexity of the immune system, it is not surprising that multiple self-regulatory mechanisms are organized at different levels, such as antibody feedback, idiotypic-anti-idiotypic responses, suppres- sor and helper T cells, lymphokine signals and genetic require- ments. A nu mb er of observations in recent years have, however, demonstrated that consistent contributions to the immunological homeostasis are given also by signals generated outside of the immune system, namely, in the central and autonomous nervous system as weIl as in the endocrine apparatus. Furthermore, the interactions between the immune system and the other body homestatic mechanisms seem to be bidirectional: if immunological cells may be targets of neuroendocrinological factors, immunological products seem in turn to contribute to the neuro- endocrine homeostasis.

Book details

SKU NLS9781468445497
ISBN 13 9781468445497
ISBN 10 1468445499
Author Nicola Fabris
Condition New
Binding Type Paperback
Publisher Springer-Verlag New York Inc.
Year published 2012-03-14
Number of pages 478
Cover note Book picture is for illustrative purposes only, actual binding, cover or edition may vary.

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