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| Language | English |
| Format | PDF (Premium Digital) |
| Ownership | Permanent download — yours forever |
Immunology, Phenotype First: How Mutations Have Established New Principles and Pathways in Immunology by Bruce Beutler
This monograph deals with the impact of classical genetics in immunology, prov- ing examples of how large immunological questions were solved, and new fields opened to analysis through the study of phenotypes, either spontaneous or induced. As broad as biology has become, there are those who do not fully understand what the genetic approach is, and how it differs fundamentally from most of the methods available to natural scientists. They may hold the opinion that genetics has run its course since Mendel read his paper on peas in 1865. Why bother with classical genetics, they may ask. Won't all genes be knocked out soon anyway? Or they are intimidated by genetics, with its heavy reliance on model organisms that seem so alien. What has C. elegans to do with me? the questioning might go. It doesn't even have lymphocytes. Such skeptics may be unaware that the mouse is fast becoming as tractable a model organism as the fly, and that humans may not be too far behind. So I would like to introduce the topic with a few words about the power of genetics, and why it has contributed so much to immunology, and to bi- ogy in general. Genetics, as the word is used here, is not merely the science of heredity, but much more than that. It is the science of exceptions: the science that takes note of heritable variation and seeks to explain it at the most fundamental level.| ISBN 13 | 9783540752028 |
|---|---|
| ISBN 10 | 3540752021 |
| Author | Bruce Beutler |
| Series | Current Topics In Microbiology And Immunology |
| Condition | New |
| Binding Type | Hardback |
| Publisher | Springer |
| Year published | 2008-07-21 |
| Number of pages | 220 |
| Cover note | Book picture is for illustrative purposes only, actual binding, cover or edition may vary. |
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"I compared Kindle vs this store. Kindle is cheaper monthly but you don't own anything. Here I paid once and the PDF is mine for life. Highly recommend."
"Left Kindle behind after they removed a book I was reading mid-series. With this PDF, nobody can take it away from me. True ownership feels good."
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"My Kindle subscription was getting expensive. Switched to buying PDFs here and I'm saving money while actually building a permanent digital library I control."
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