Gewebs- und Neurohormone by Henryk Nowakowski ISBN 9783540029090
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Gewebs- und Neurohormone by Henryk Nowakowski ISBN 9783540029090

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Gewebs- und Neurohormone by Henryk Nowakowski

Man kann zwei experimentell erzengbare Formen von Strumen unterscheiden. Die eine, der Pr basedowkropf, wird repr sentiert durch den Kohlkropf, der durch Verf tterung von Kohl oder hnlichen pflanzlichen Noxentr gern entsteht. Die zweite Kropfart wird repr sentiert durch die unter dem Einflu von Schwefel- pr paraten, wie Thioharnstoff, Thiouracil, und anderen organischen und anorga- nischen Schwefelverbindungen entstehende degenerative Struma. Die durch Ver- f tterung von Kohl entstehende Pr basedowstruma wird durch Hinzutreten des Jodions zur eigentlichen Basedowstruma, w hrend der degenerative Schwefel- kropf auf das zugef hrte Jodion nicht anspricht. Das Kennzeichen des degenera- tiven Kropfes ist neben der Vergr erung der Schilddr se die fortschreitende bis totale Aufhebung ihrer Lebenst tigkeit, bedingt durch eine allm hliche bis v llige Vernichtung der spezifischen Jodaseeigenschaft dieser Dr se. Im Gegensatz zum Kohlkropf, der dauernd auf Jodion anspricht, verliert der degenerative Kropf nach und nach jegliche F higkeit, Jodion zu verarbeiten und Jodeiwei auf- zubauen. F r die Entstehung des Kohlkropfes bezeichnet F. BLUM eine Blockierung der besonders in der Leber vorhandenen Dejodase als Ursache. Er sieht in dem blockierten Agens die f r diese experimentell erzeugte Strumaform verantwort- liche Kropfnoxe. Die Jodfehlverwertung bei der degenerativen Struma ist durch eine die Jodase sch digende Beeinflussung bedingt. Literatur I. KLEIN, E. : Der endogene Jodhaushalt des Menschen und seine St rungen. Stuttgart: Georg Thieme-Verlag I960. 2. BLUM, F. : Studium zum Kropfproblem. Schweiz. med. Wschr. 83, 5I3 (I953). 3. -, u. W. TATERKA: Mikrobiologische Probleme zur tiologie des endemischen Kropfes. Schweiz. Z. Path. 18, 32 (I955). 4. - - Beitr ge zur tiologie des degenerativen Kropfes. Schweiz. Z. Path. 20, 577 (I957).

Book details

SKU NLS9783540029090
ISBN 13 9783540029090
ISBN 10 3540029095
Author Henryk Nowakowski
Series Symposion Der Deutschen Gesellschaft Für Endokrinologie
Condition New
Binding Type Paperback
Publisher Springer
Year published 1962-01-01
Number of pages 457
Cover note Book picture is for illustrative purposes only, actual binding, cover or edition may vary.

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