Genome Editing by Toni Cathomen ISBN 9781493980611
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Genome Editing by Toni Cathomen ISBN 9781493980611

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Genome Editing by Toni Cathomen

This comprehensive volume explores human genetic engineering its pre-clinical and clinical applications, current developments, and as treatment for hereditary diseases. It presents and evaluates the most recent advances in the understanding of mammalian host DNA repair mechanisms, such as double-strand break induced gene targeting and mutagenesis, the development of zinc-finger nucleases, genome editing for neuromuscular diseases, phase integrases, triplex forming oligonucleotides and peptide nucleic acids, aptamer-guided gene targeting, AAV gene editing via DSB repair, engineered nucleases and trinucleotide repeat diseases, and creation of HIV-resistant cells. The expertly authored chapters contextualize current developments within the history of genome editing while also discussing the current and potential safety concerns of this rapidly growing field.

Genome Editing: The Next Step in Gene Therapy, the latest volume in the American Society of Gene and Cell Therapy series, deftly illuminates the potential of genetic engineering technology to eradicate today’s deadliest and most prolific diseases. It is ideal reading for clinicians and researchers in genetics and immunology.

Book details

SKU NLS9781493980611
ISBN 13 9781493980611
ISBN 10 1493980610
Author Toni Cathomen
Series Advances In Experimental Medicine And Biology
Condition New
Binding Type Paperback
Publisher Springer-Verlag New York Inc.
Year published 2018-04-08
Number of pages 263
Cover note Book picture is for illustrative purposes only, actual binding, cover or edition may vary.

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