Fibrosis Research by John Varga ISBN 9781617375927
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Fibrosis Research by John Varga ISBN 9781617375927

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Fibrosis Research by John Varga

Leading investigators review the highlights of current fibrosis research and the experimental methodologies used uncover the mechanisms that drive it. In their discussion of research methodologies utilizing cultured cells to model various aspects of the fibrotic response in vitro, the authors describe the isolation, characterization, and propagation of mesenchymal cells, and highlight the similarities and differences between methods that are appropriate for different types of fibroblasts. Approaches for studying collagen gene regulation and TGF-b production are also discussed, along with experimental methodologies utilizing animal models to study the pathogenesis of fibrosis. The protocols follow the successful Methods in Molecular Medicine(tm) series format, each offering step-by-step laboratory instructions, an introduction outlining the principles behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls.

Book details

SKU NLS9781617375927
ISBN 13 9781617375927
ISBN 10 1617375926
Author John Varga
Series Methods In Molecular Medicine
Condition New
Binding Type Paperback
Publisher Humana Press Inc.
Year published 2010-11-10
Number of pages 392
Cover note Book picture is for illustrative purposes only, actual binding, cover or edition may vary.

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