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| Language | English |
| Format | PDF (Premium Digital) |
| Ownership | Permanent download — yours forever |
Extrasynaptic GABAA Receptors by Adam C Errington
GABA is the principal inhibitory neurotransmitter in the CNS and acts via GABA and GABAB receptors. Recently, a novel form of GABA receptor-mediated inhibition, termed tonic inhibition, has been described. Whereas synaptic GABA receptors underlie classical phasic GABA receptor-mediated inhibition (inhibitory postsynaptic currents), tonic GABA receptor-mediated inhibition results from the activation of extrasynaptic receptors by low concentrations of ambient GABA. Extrasynaptic GABA receptors are composed of receptor subunits that convey biophysical properties ideally suited to the generation of persistent inhibition and are pharmacologically and functionally distinct from their synaptic counterparts. This book highlights ongoing work examining the properties of recombinant and native extrasynaptic GABA receptors and their preferential targeting by endogenous and clinically relevant agents. In addition, it emphasizes the important role of extrasynaptic GABA receptors in GABAergic inhibition throughout the CNS and identifies them as a major player in both physiological and pathophysiological processes.| SKU | NLS9781493914258 |
|---|---|
| ISBN 13 | 9781493914258 |
| ISBN 10 | 1493914251 |
| Author | Adam C Errington |
| Series | The Receptors |
| Condition | New |
| Binding Type | Hardback |
| Publisher | Springer-Verlag New York Inc. |
| Year published | 2014-09-23 |
| Number of pages | 295 |
| Cover note | Book picture is for illustrative purposes only, actual binding, cover or edition may vary. |
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"Kindle Unlimited kept raising prices. This is a one-time purchase and the file is permanently on my iPad. Best decision I've made for my reading habit."
"I compared Kindle vs this store. Kindle is cheaper monthly but you don't own anything. Here I paid once and the PDF is mine for life. Highly recommend."
"Left Kindle behind after they removed a book I was reading mid-series. With this PDF, nobody can take it away from me. True ownership feels good."
"Was skeptical about paying $18.95 when Kindle shows $3.99, but then I did the math — Kindle Unlimited is $143/year! This is way better value long term."
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