Energy Balance and Hematologic Malignancies by Steven D Mittelman ISBN 9781461424024
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Energy Balance and Hematologic Malignancies by Steven D Mittelman ISBN 9781461424024

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Energy Balance and Hematologic Malignancies by Steven D Mittelman

The obesity pandemic continues to increase on a world-wide basis with over 70% of the United States population being either overweight or obese. Hematologic malignancies have recently been identified among the obesity associated malignancies spanning the lifespan from childhood to the elderly and include leukemia, myeloma, lymphoma and others. In addition to the etiologic association between obesity and hematologic malignancies, the presence of obesity has profound effects on therapy by impacting pharmacokinetics of chemotherapeutic agents, dose, adipocyte metabolism and drug distribution. These may be particularly important in hematopoietic stem cell transplantation. Another important aspect of the association of obesity with hematologic malignancies is the increased incidence of obesity in children who successfully complete therapy for acute lymphoblastic leukemia. This and other observations indicate important relations between the hematopoietic systems and fat metabolism. This volume on Energy Balance in Hematologic Malignancies will provide an important volume in this series and a basis for better understanding etiology, mechanisms, therapeutics implications and experimental approaches. This volume of energy balance and cancer will focus on the relation of obesity to hematologic malignancies, the epidemiology, potential mechanisms, and thereapeutic considerations including effects on pharmacologic and physical approaches as well as the delayed effects of therapy on energy balance.

Book details

SKU NLS9781461424024
ISBN 13 9781461424024
ISBN 10 146142402X
Author Steven D Mittelman
Series Energy Balance And Cancer
Condition New
Binding Type Hardback
Publisher Springer-Verlag New York Inc.
Year published 2012-02-28
Number of pages 186
Cover note Book picture is for illustrative purposes only, actual binding, cover or edition may vary.

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