Duchenne Muscular Dystrophy by Camilla Bernardini ISBN 9781493973736
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Duchenne Muscular Dystrophy by Camilla Bernardini ISBN 9781493973736

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Duchenne Muscular Dystrophy by Camilla Bernardini

This volume explores experimental approaches used to study Duchenne muscular dystrophy (DMD), an X-linked degenerative skeletal muscle disease caused by mutations in the dystrophin gene. Including the latest progress and scientific achievements, the book covers recent discoveries achieved through in vivo gene editing which have proven to be promising in restoring dystrophin expression, at least in ameliorating skeletal muscle symptoms, and the contents focus on “Omics” techniques in gene expression, protein expression, miRNAs, and long non-coding RNA analysis, as well as experimental studies of the structural/functional changes affecting the skeletal and cardiac muscles and ongoing preclinical studies and clinical trials. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshootingand avoiding known pitfalls.
Authoritative and practical, Duchenne Muscular Dystrophy: Methods and Protocols serves as a guide for researchers exploring the complicated nature of dystrophin in the hope of helping the victims of this disorder.

Book details

SKU NLS9781493973736
ISBN 13 9781493973736
ISBN 10 1493973738
Author Camilla Bernardini
Series Methods In Molecular Biology
Condition New
Binding Type Hardback
Publisher Humana Press Inc.
Year published 2017-10-25
Number of pages 287
Cover note Book picture is for illustrative purposes only, actual binding, cover or edition may vary.

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