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| Language | English |
| Format | PDF (Premium Digital) |
| Ownership | Permanent download — yours forever |
DNA Methylation and Cancer by Pa Jones
This book is a comprehensive survey of new and exciting developments regarding the role of DNA methylation in human cancer. Issues related to the mutagenicity of 5-methylcytosine and the increase in the interaction of chemical and physical carcinogens with these residues is discussed. The book summarizes the modulation of viral gene expression and the silencing of tumor suppressor genes and illustrates mechanisms by which the methylation signal is translated into altered chromatin structure. The relationship between DNA methylation and genomic imprinting and cancer, and changes in CpG island methylation which occur in aging are discussed. Mouse model systems have played a key role in our dissection of the relationship between methylation and cancer, and these are also portrayed together with descriptions of new clinical trials in which methylation inhibitors are being used to treat leukemia, myeloid dysplastic syndromes and hemoglobinopathies.| ISBN 13 | 9783642640902 |
|---|---|
| ISBN 10 | 3642640907 |
| Author | Pa Jones |
| Series | Current Topics In Microbiology And Immunology |
| Condition | New |
| Binding Type | Paperback |
| Publisher | Springer-Verlag Berlin and Heidelberg GmbH & Co. KG |
| Year published | 2011-09-22 |
| Number of pages | 170 |
| Cover note | Book picture is for illustrative purposes only, actual binding, cover or edition may vary. |
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"Kindle Unlimited kept raising prices. This is a one-time purchase and the file is permanently on my iPad. Best decision I've made for my reading habit."
"I compared Kindle vs this store. Kindle is cheaper monthly but you don't own anything. Here I paid once and the PDF is mine for life. Highly recommend."
"Left Kindle behind after they removed a book I was reading mid-series. With this PDF, nobody can take it away from me. True ownership feels good."
"Was skeptical about paying $18.95 when Kindle shows $3.99, but then I did the math — Kindle Unlimited is $143/year! This is way better value long term."
"Love that I can read this on any device without installing the Kindle app. The PDF works on my laptop, phone, and tablet seamlessly. So much freedom."
"My Kindle subscription was getting expensive. Switched to buying PDFs here and I'm saving money while actually building a permanent digital library I control."
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