{"product_id":"dna-alterations-in-lynch-syndrome-by-matjaz-vogelsang","title":"DNA Alterations in Lynch Syndrome by Matjaz Vogelsang | ISBN-13 9789401784580","description":"\u003cp\u003eExplore \u003cstrong\u003eDNA Alterations in Lynch Syndrome by Matjaz Vogelsang\u003c\/strong\u003e by Matjaz Vogelsang, a valuable resource for readers seeking subject knowledge, key concepts, and a deeper understanding of the topic.\u003c\/p\u003e\u003cp\u003eDNA Alterations in Lynch Syndrome by Matjaz Vogelsang Lynch syndrome (LS) is the most common cause of inherited colorectal cancer, a disease with a high mortality rate. An estimated 37,000 of diagnosed colorectal cancer cases worldwide are attributed to Lynch syndrome each year. Intensive cancer screening, with early initiation and frequent follow-up, can reduce colorectal cancer incidence and mortality in LS patients. This book provides an up-to-date overview on the genetic and epigenetic basis of Lynch syndrome. It evaluates clinical features of the disease and critically comments on molecular tools available for identifying mutations responsible for Lynch syndrome; in addition the importance of functional assays that can help clarify the clinical nature of identified mutations is also discussed. The book also focuses on challenges in genetic counselling of at-risk individuals and discusses related ethical issues. The purpose of the book is to give a concise knowledge base for the broader scientific and medical community, including genetic counselors, in order to improve awareness on the potential impact that the diagnosis of LS has on treatment, management and surveillance of LS patients.\u003c\/p\u003e\u003ch3\u003eBook details\u003c\/h3\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eISBN-13:\u003c\/strong\u003e 9789401784580\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAuthor:\u003c\/strong\u003e Matjaz Vogelsang\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePublisher:\u003c\/strong\u003e Springer\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePublication year:\u003c\/strong\u003e 2015\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePages:\u003c\/strong\u003e 195\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eElectronic edition. Please review the product details before purchase to confirm this format meets your needs.\u003c\/p\u003e","brand":"Springer","offers":[{"title":"Default Title","offer_id":67681954169077,"sku":null,"price":39.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0795\/8632\/8821\/files\/9789401784580.jpg?v=1791822465","url":"https:\/\/arbiyas.com\/products\/dna-alterations-in-lynch-syndrome-by-matjaz-vogelsang","provider":"Arbiyas","version":"1.0","type":"link"}