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| Language | English |
| Format | PDF (Premium Digital) |
| Ownership | Permanent download — yours forever |
CNS Neuroprotection by Frank W Marcoux
CNS neuroprotection was a common subject of papers, symposia, and reviews during the previous decade of the brain. Indeed, in recent years, experimental study of putative neuroprotective agents prompted clinical trials of numerous drug candidates in acute and chronic human neurodegenerative conditions. While the outcomes of these trials have not been as successful as initially hoped, these were early explorations, and the pipeline of relevant ideas continues to grow in strength and depth. We predict that early in this new millennium, crippling disorders such as stroke and Alzheimer's disease will be treated effectively by therapeutic neuroprotective strategies. This volume of the Handbook of Experimental Pharmacology titled eNS Neuroprotection provides a pharmacological perspective on currently promis- ing neuroprotective approaches, and a clinical perspective on the challenges involved in establishing the efficacy of these approaches through appropriate clinical trials. Section I, Mechanistic Approaches to CNS Neuroprotection, reviews major injury mechanisms that have formed the basis for many past and present clinical trials conducted around the world. Dr. KIM and colleagues, Washington University School of Medicine, review the status of blocking excitotoxicity as an approach to CNS neuroprotection. Dr. WANG, Pfizer Global Research and Development, Ann Arbor Laboratories, outlines evidence supporting a contri- bution of apoptosis to pathological neuronal or glial cell loss. Drs. BECKER and HALENBECK, University of Washington and the National Institute on Neuro- logical Diseases and Stroke, respectively, argue that inhibiting inflammatory pathways in the brain can be neuroprotective. Dr.| ISBN 13 | 9783540424123 |
|---|---|
| ISBN 10 | 3540424121 |
| Author | Frank W Marcoux |
| Series | Handbook Of Experimental Pharmacology |
| Condition | New |
| Binding Type | Hardback |
| Publisher | Springer |
| Year published | 2002-07-10 |
| Number of pages | 500 |
| Cover note | Book picture is for illustrative purposes only, actual binding, cover or edition may vary. |
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"Kindle Unlimited kept raising prices. This is a one-time purchase and the file is permanently on my iPad. Best decision I've made for my reading habit."
"I compared Kindle vs this store. Kindle is cheaper monthly but you don't own anything. Here I paid once and the PDF is mine for life. Highly recommend."
"Left Kindle behind after they removed a book I was reading mid-series. With this PDF, nobody can take it away from me. True ownership feels good."
"Was skeptical about paying $18.95 when Kindle shows $3.99, but then I did the math — Kindle Unlimited is $143/year! This is way better value long term."
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