Cancer Immunotherapy at the Crossroads by James H Finke ISBN 9781468498448
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Cancer Immunotherapy at the Crossroads by James H Finke ISBN 9781468498448

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Cancer Immunotherapy at the Crossroads by James H Finke

Leading investigators and clinicians detail the different mechanisms used by tumors to escape and impair the immune system and then spell out possible clinical strategies to prevent or reverse tumor-induced immune dysfunction. The authors review the mechanisms of immune dysfunction and evasion mechanisms in histologically diverse human tumors, focusing on tumor-induced molecular defects in T cells and antigen-presenting cells (dendritic cells and tumors), that may serve as biomarkers for patient prognosis. They discuss the means by which these immune functions may be protected or restored in order to more effectively support the process of tumor rejection in situ. Cutting-edge techniques are outlined with the capacity to monitor the strength and quality of patients' immune responses using immunocytometry, MHC-peptide tetramers combined with apoptosis assay, ELISPOT assay, and detection of MHC-TAA peptide complexes on tumor cells.

Book details

SKU NLS9781468498448
ISBN 13 9781468498448
ISBN 10 1468498444
Author James H Finke
Series Current Clinical Oncology
Condition New
Binding Type Paperback
Publisher Humana Press Inc.
Year published 2012-08-02
Number of pages 386
Cover note Book picture is for illustrative purposes only, actual binding, cover or edition may vary.

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