Behavioral Neurobiology of Huntington's Disease and Parkinson's Disease by Hoa Huu Phuc Nguyen | ISBN-13 9783662524121
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Behavioral Neurobiology of Huntington's Disease and Parkinson's Disease by Hoa Huu Phuc Nguyen | ISBN-13 9783662524121

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Behavioral Neurobiology of Huntington's Disease and Parkinson's Disease by Hoa Huu Phuc Nguyen

Motor dysfunction and cognitive impairment are major symptoms in both Huntington's Disease (HD) and Parkinson's Disease (PD). A breakthrough in HD research was the identification of the gene that causes this devastating monogenetic illness. Similarly, several genes were found to cause familial forms of PD. With their identification, a plethora of genetic animal models has been generated and has revolutionized the understanding of the pathobiology and pathophysiology of these disorders. The models allow us to study the earliest manifestations of the diseases behaviorally and neuropathologically and help us understand how they progress over time. Additionally, neurotoxic animal models are still of high interest to the PD field, as they are being used to study e.g. mitochondrial dysfunction in PD. This book focuses on animal models of both diseases and how they have helped and will continue to help understand the behavioral neurobiology in these disorders.

Book details

ISBN 13 9783662524121
ISBN 10 3662524120
Author Hoa Huu Phuc Nguyen
Series Current Topics In Behavioral Neurosciences
Condition New
Binding Type Paperback
Publisher Springer
Year published 2016-10-29
Number of pages 397
Cover note Book picture is for illustrative purposes only, actual binding, cover or edition may vary.

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