Aging in Cell and Tissue Culture by E Holeckova ISBN 9781468418231
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Aging in Cell and Tissue Culture by E Holeckova ISBN 9781468418231

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Aging in Cell and Tissue Culture by E Holeckova

The annual meeting of the European Tissue Culture., Society was held at the Castle of Zinkovy in Czechoslovakia from May 7-10,1969. Included as part of this meeting was a symposium on Aging in Cell and Tissue Culture. This volume contains the papers presented at that symposium. The use of cell and tissue culture techniques to study the mechanism of aging is not new. For example, it has long been known that age-associated changes which occur in plasma can inhibit cell proliferation in vitro; also that the time lapse prior to cell migration from ex- planted tissue fragments increases with increasing age. These are both examples of the expression in vitro of aging in vivo. More recently, attention has been focused on the occurrence of senescence in vitro. These investi- gations have included studies of alterations in non- dividing cell cultures, and to a somewhat greater extent, of age-related changes in the proliferative capacity of cells in vitro. For example, cells derived from human fetal lung retain many properties of normal cells including a stable normal diploid karyotype and these cultures have been shown to have a limited life-span in vitro. In addi- tion, cultures derived from human adult lung show the same normal characteristics and appear to have a shorter life- span than cells derived from fetal lung.

Book details

SKU NGR9781468418231
ISBN 13 9781468418231
ISBN 10 1468418238
Author E Holeckova
Condition New
Binding Type Paperback
Publisher Springer-Verlag New York Inc.
Year published 2012-03-28
Number of pages 164
Cover note Book picture is for illustrative purposes only, actual binding, cover or edition may vary.

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