{"product_id":"admixture-dynamics-natural-selection-and-diseases-in-admixed-populations-by-wenfei-jin","title":"Admixture Dynamics, Natural Selection and Diseases in Admixed Populations by Wenfei Jin | ISBN-13 9789402404302","description":"\u003cp\u003eExplore \u003cstrong\u003eAdmixture Dynamics, Natural Selection and Diseases in Admixed Populations by Wenfei Jin\u003c\/strong\u003e by Wenfei Jin, a valuable resource for readers seeking subject knowledge, key concepts, and a deeper understanding of the topic.\u003c\/p\u003e\u003cp\u003eAdmixture Dynamics, Natural Selection and Diseases in Admixed Populations by Wenfei Jin In this thesis, Dr. Jin presents the distribution of ancestral chromosomal segments in the admixed genome, which could provide the information needed to explore population admixture dynamics. The author derives accurate population histories of African Americans and Mexicans using genome-wide single nucleotide polymorphisms (SNPs) data. Mapping the genetic background facilitates the study of natural selection in the admixed population, and the author identifies the signals of selection in African Americans since their African ancestors left for America. He further demonstrates that many of the selection signals were associated with African American-specific high-risk diseases such as prostate cancer and hypertension, suggesting an important role these disease-related genes might have played in adapting to their new environment. Lastly, the author reveals the complexity of natural selection in shaping human susceptibility to disease. The thesis significantly advances our understanding of the recent population admixture, adaptation to local environment and its health implications.\u003c\/p\u003e\u003ch3\u003eBook details\u003c\/h3\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eISBN-13:\u003c\/strong\u003e 9789402404302\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAuthor:\u003c\/strong\u003e Wenfei Jin\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePublisher:\u003c\/strong\u003e Springer\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePublication year:\u003c\/strong\u003e 2016\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePages:\u003c\/strong\u003e 114\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eElectronic edition. Please review the product details before purchase to confirm this format meets your needs.\u003c\/p\u003e","brand":"Springer","offers":[{"title":"Default Title","offer_id":67681938833653,"sku":null,"price":39.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0795\/8632\/8821\/files\/9789402404302.jpg?v=1791822343","url":"https:\/\/arbiyas.com\/products\/admixture-dynamics-natural-selection-and-diseases-in-admixed-populations-by-wenfei-jin","provider":"Arbiyas","version":"1.0","type":"link"}